Natural Fat Transfer and LMK NanoStem Serum 



Natural Fat Transfer using NanoStem Serum (NSS) is a very important component of your facial rejuvenation journey. To directly improve skin quality and tone, we create a serum from your body’s own fat cells. This serum is injected into the skin to create a healthier, more youthful complexion. Most essential to a successful procedure is working with a well-trained, experienced plastic surgeon who will artistically and carefully place your injections. 

The procedure is safe and simple—no incisions or surgery involved. It also has a quick recovery time. The results of this procedure are a smoother, healthier, and younger looking complexion. Usually, Natural Fat Transfer is employed in conjunction with liposuction because fat is already being removed, and this way it can have an additional benefit to smooth and cushion the desired area. Natural Fat Transfer and NanoStem Serum are also performed as stand-alone procedures to artfully rejuvenate faces, earlobes, and hands. 

Stem cells reside in fat as well as other tissues in the body. The process of actively extracting, concentrating and administering these fat-derived stem cells has been proven in medical studies to have beneficial effects, and its function as an aesthetic filler under skin is well-documented (1). There is very little risk for negative effects of using fat as a filler because no one is allergic to their own fat.


First, a physician extracts natural, healthy fat cells from under your skin using liposuction. The fat layer resides below the dermis and epidermis (skin) layers. Removing fat from an unwanted area is an added benefit of NSS.  

The key to this procedure is a gentle extraction of the fat. The fat is then washed and excess water is removed. Then it is put into a Nano Emulsifier and run through a Nano Filter to be processed and concentrated. 

The washed, emulsified, and filtered fat is then centrifuged, where it separates into oil, particulate fraction, and liquid fraction.  

The separated elements are now ready for injection. The physician should take care to make sure that the bed where the fat is to be injected will accept the new fat and allow it to thrive. This procedure is all about skillful and artistic technique—be confident that your medical professional will not place your fat in a lumpy or unnatural-looking way.  

To fill deeper lines, particulate fraction is injected. Liquid fraction treats the finer lines. The results will be a smoother texture, less visible wrinkles, healthier skin color, and cushioning and support for the epidermal layer. The results should be permanent when done properly. The injected fat that thrives will have a continuous blood supply, so with a well-executed procedure the extra volume provided by fat transfer should last for many years (2). NSS has more permanent results than injectable fillers which require reinjection to maintain the benefits (2). 

Dr. Koplin has been doing the Natural Fat Transfer procedure for more than 20 years and has participated in the recent development and refinement of NanoStem Serum techniques. He holds a double board certification in both General Surgery and Plastic Surgery, and is regarded as an innovative artist in the field of plastic surgery. An expert and perfectionist, Dr. Koplin’s top priority is to craft a youthful, natural-looking elegance.  Read more or watch a video from Dr. Koplin.

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1. George KH Li, Joseph HP Chung, Lawrence HL Lieu, Velda LY Chow, Gregory Ian SK Lau, and Richie CL Chan, “Fat grafting: A safe and effective treatment of craniofacial depression,” Surgical Practice 19, no. 2 (May 2015):75-81, 

2. West County Plastic Surgeons of Washington University, “Fat Grafting,”, 2015.